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Cat. No. | Product Name | Target | Signaling Pathways |
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T69361 |
C16-Urea-Ceramide
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C16-Urea-Ceramide s a neutral ceramidase (nCDase) inhibitor. It is a bioactive ceramide. | |||
T36321 |
C6 Urea Ceramide
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C6 urea ceramide is an inhibitor of neutral ceramidase.1 It increases total ceramide levels in wild-type mouse embryonic fibroblasts (MEFs) and in HT-29 colon cancer cells but not in MEFs lacking neutral ceramidase. It inhibits proliferation of, and induces apoptosis and autophagy in HT-29, but not non-cancerous RIE-1, cells when used at concentrations of 5 and 10 μM. C6 urea ceramide decreases total β-catenin, increases phosphorylated β-catenin, and induces colocalization of β-catenin with the ... |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01771 |
ASAH2 Protein, Human, Recombinant (His)
HNAC1,LCDase (hCD),BCDase,Non-lysosomal ceramidase,... |
Human | E. coli |
ASAH2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9NR71. | |||
TMPH-01985 |
ASAH2B Protein, Human, Recombinant (His)
ASAH2L,ASAH2B,Putative inactive non-lysosomal ceramidase... |
Human | E. coli |
N/A. ASAH2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C7U1. | |||
TMPY-00963 |
ASAH2 Protein, Mouse, Recombinant (His)
N-acylsphingosine amidohydrolase (non-lysosomal ceramida... |
Mouse | HEK293 Cells |
ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 po... |